Accropeutics has fostered a robust portfolio of innovative compounds spanning from lead optimization to clinical development.
AC-101 (RIPK2 inhibitor)
Completed Phase I clinical studies in Australia and China. Outstanding safety and PK/PD profiles achieved,currently undergoing a Phase Ib trial in Ulcerative Colitis (UC) patients in China,obtained FDA clearance for a phase II MRCT study for the treatment of IBD patients.
AC-201 (a selective TYK2/JAK1 pseudo kinase inhibitor)
"Pipeline-in-a-Product" potential for treating inflammatory and autoimmune diseases, completed Phase I study in Australia and China, completed a phase II clinical trial for patients with moderate to severe plaque psoriasis in China,granted to Fosun Pharma exclusive rights in Mainland China, Hong Kong, and Macau.
AC-003 (RIPK1 inhibitor)
completed Phase I clinical trials in China and the United States,currently undergoing a Phase Ib clinical trial in aGVHD patients in China,obtained Orphan Drug Designation (ODD) from the FDA.
The Company has multiple compounds in the PCC and preclinical research stages. The Company owns more than 20 patents issued in major markets including the US, the EU, China, Japan, and Korea.